MOLECULAR DIVERSITY OF PAENIBACILLUS LARVAE STRAINS ISOLATED FROM LITHUANIAN APIARIES


Alignment independent 3D-QSAR, quantum calculations and molecular docking of Mer specific tyrosine kinase inhibitors as anticancer drugs

Mer receptor tyrosine Vehicle Parts kinase is a promising novel cancer therapeutic target in many human cancers, because abnormal activation of Mer has been implicated in survival signaling and chemoresistance.3D-QSAR analyses based on alignment independent descriptors were performed on a series of 81 Mer specific tyrosine kinase inhibitors.The fra

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Yessotoxin, a Marine Toxin, Exhibits Anti-Allergic and Anti-Tumoural Activities Inhibiting Melanoma Tumour Growth in a Preclinical Model.

Yessotoxins (YTXs) are a group of marine toxins produced by the dinoflagellates Protoceratium reticulatum, Lingulodinium polyedrum and Gonyaulax spinifera.They may have medical interest due to their potential role as anti-allergic but also anti-cancer compounds.However, their biological activities remain poorly characterized.Here, we show that the

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Security Face of Human Rights Conflict of Iran and West

Human Rights issue, is among the fundamental achievements of the international relations and law.The Islamic Republic of Iran, as an actor with different norms and ideologies than the norms that shape human rights, has always been exposed to various accusations by Super Chaise human rights activists and institutions.To the extent that this issue ha

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